GAK inhibitor 49 - Names and Identifiers
GAK inhibitor 49 - Physico-chemical Properties
Molecular Formula | C20H22N2O5
|
Molar Mass | 370.4 |
Density | 1.223±0.06 g/cm3(Predicted) |
Boling Point | 494.8±45.0 °C(Predicted) |
pKa | 7?+-.0.50(Predicted) |
Storage Condition | -20℃ |
In vitro study | GAK inhibitor 49 (compound 49) shows a weak inhibitory effect on AAK1, BMP2K and STK16, with IC 50 s of 28, 63 and >100 μM, respectively. |
GAK inhibitor 49 - Preparation solution concentration reference
| 1mg | 5mg | 10mg |
---|
1 mM | 0 ml | 0 ml | 0 ml |
5 mM | 0 ml | 0 ml | 0 ml |
10 mM | 0 ml | 0 ml | 0 ml |
5 mM | 0 ml | 0 ml | 0 ml |
Last Update:2024-01-02 23:10:35
GAK inhibitor 49 - Reference Information
biological activity | GAK inhibitor 49 is an ATP-competitive, highly selective cyclin G-related kinase (GAK) inhibitors, Ki is 0.54 nM, cell IC50 is 56 nM. GAK inhibitor 49 was also shown to bind to ripk2. |
Last Update:2024-04-09 22:09:11